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Causes of Leg Pain and Foot Pain

Leg Pain

Leg and foot pain varies in type and severity and usually depends on an individual's lifestyle and associated medical issues. In addition to leg pathology, leg discomfort may be triggered by a condition affecting the lower back, hip, or pelvic region. The kind of pain might differ based on the underlying cause.

This article supplies a guide to the possible causes, specific diagnostic procedures, and the various kinds of treatment approaches readily available for leg and foot pain.

Spinal Causes of Leg Pain

Problems in the lower spine may affect the spinal nerve roots, causing pain to radiate into the leg and foot (radiculopathy). Common causes of leg and foot pain that originate in the spine include:

  • Spinal stenosis: Narrowing of the small bony openings (foramina) for spinal nerves.
  • Spondylolisthesis: Forward or backward slipping of a vertebra over the next lower vertebra.
  • Herniated discs: Bulging or leaking out of an intervertebral disc's inner contents (nucleus pulposus).
  • Degeneration: Arthritic or age-related changes in a disc, vertebral bone, or vertebral facet joint.

Compression of the spinal cord in the neck and cauda equina in the lower back can also cause leg pain


Blood Vessel Causes of Leg Pain

The arteries and veins in the legs may get inflamed or blocked, causing leg and foot pain. Common causes include:

  • Peripheral artery disease: Decreased circulation caused due to blocked arteries.
  • Deep vein thrombosis: Blood clot in the deep vein(s) of the leg causing decreased or altered blood flow.
  • Superficial thrombophlebitis: Blood clots in the superficial veins of the leg causing varicose veins or spider veins to form underneath the skin surface.

Blood vessels may also get ruptured and cause bleeding within the tissue spaces of the leg, causing acute pain and swelling.

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Pelvis and Hip Related Causes of Leg Pain

Pain from the joints and muscles of the pelvis and hip may be referred into the legs. Common causes include:

  • Piriformis syndrome: Spasm of the piriformis muscle in the pelvis impinging the sciatic nerve.
  • Sacroiliac joint dysfunction: Abnormal motion or malalignment of the sacroiliac joint.
  • Hip osteoarthritis: Wear-and-tear arthritis of the hip joint.
  • Trochanteric bursitis: Inflammation of a fluid-filled sac (bursa) on the side of the hip.

Pelvic bone fractures or other hip joint problems due to trauma, overuse, or degeneration may also cause leg pain.


Leg Pain

Leg Pain due to Nerve Damage

Certain medical conditions may cause damage to the peripheral nerves in the leg. Common causes are:

  • Metabolic disorders, such as type 2 diabetes mellitus or hypothyroidism.
  • Infections include bacterial infection of the vertebral bone and disc, epidural abscess (accumulation of pus in the epidural space surrounding the spinal cord), herpes zoster, HIV, and/or Lyme disease.

Rarely, autoimmune conditions such as Guillain-Barré syndrome, where the body's immune system attacks the peripheral nervous system, may cause leg pain.

Nutritional Causes of Leg Pain

Deficiency of specific vitamins and minerals may cause damage to the peripheral nerves (peripheral neuropathy), resulting in leg pain and weakness. Typical nutrient deficiencies include:

  • Vitamin B12
  • Vitamin B6
  • Copper

Excessive intake of alcohol and heavy metals, such as arsenic, thallium, or mercury, may also cause peripheral nerve damage and pain in the legs.

Causes of Foot Pain and Numbness

Certain conditions may cause pain and numbness in the foot with or without leg pain. Foot pain commonly occurs in:

  • Tarsal tunnel syndrome: Compression of the tibial nerve due to trauma, swelling, poorly fitting shoes, tendon problems, or enlarged arteries or veins.
  • Peroneal neuropathy: Compression of the peroneal nerve due to trauma, tumors, or other systemic conditions.
  • Sural nerve entrapment: Compression of the sural nerve due to tumors, scar tissue, or tight ski boots.
  • L5 and S1 radiculopathy: Compression of the L5 or S1 nerve roots in the lower back.

Severe foot weakness can cause foot drop (inability to lift the foot off the ground).


Leg Pain

Risk Factors for Leg Pain

A few risk factors associated with leg and foot pain include:

  • Advanced age
  • Genetics
  • Poor posture
  • Occupations, such as heavy labor, sports, or military service

While the listed causes and risk factors are not comprehensive, one or more of these conditions are typically associated with leg and foot pain.

Several causes of leg pain can produce overlapping signs and symptoms. It is crucial to accurately diagnose the underlying cause of leg pain to effectively treat the condition and rule out serious problems, such as tumors, infections, or nerve damage.

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